Online knowledge base:
Pharmacological Treatments of Attention Deficit Hyperactivity Disorder (ADHD)

At present this knowledge base contains information on the pharmacological treatment of ADHD, and it is intended to be used for CPD purposes.

• Mediating factors on the treatment of ADHD
  • Effect of Gender on treatment
  • Effect of Age on treatment
  • Effect of Comorbidity on treatment
    • ADHD with depressive disorder
    • ADHD with anxiety disorder
    • ADHD with chronic tic disorders
    • ADHD and Epilepsy
    • ADHD and learning disability
    • "ADHD" with or secondary to other psychiatric conditions
    • ADHD and drug misuse
    • ADHD and Illicit use of stimulants

• Genetics
• Pathophysiology
• Brain imaging studies
• Neuropsychological studies

• Pharmacological treatments (graded)
• Available Guidelines, Algorithms and Protocols
  • Evidence Based Guidelines
  • Algorithms and Protocols
  • Extended Release Preparations
  • New "modified release" preparations licensed for the treatment of ADHD in the US
• Drug therapy with Methylphenidate
  • History
    • History of Methylphenidate
    • History of drug treatments for ADHD
  • Product license information
  • Pharmacology of Methylphenidate
  • Mechanism of action
    • Dopaminergic effects of methylphenidate
    • Further information on the neurochemistry of Methylphenidate
    • Noradrenergic effects of methylphenidate
  • Pharmacokinetics
    • Absorption of methylphenidate
    • Distribution of methylphenidate
    • Metabolism of methylphenidate
    • Pharmacokinetics and dopamine transporter blockade
    • Longer acting preparations: structure and pharmokinetics
  • Pharmacodynamics
    • Relationship between the Pharmacokinetics and Pharmacodynamics
    • Effect on activity of Methylphenidate
    • Tolerance to Methylphenidate
    • Sensitization to Methylphenidate
  • Clinical effectiveness of Methylphenidate
    • Child and Adolescent
    • Adult
  • Clinical indications and usage
    • Standard indications
    • Possible indications
  • Contraindications, drug interactions & unwanted effects
    • Relative contraindications
    • Absolute Contraindications
    • Drug interactions
    • Unwanted effects and Adverse Events
      • Adverse reactions in the BNF
      • Further information on unwanted effects

• ADHD references
• Methylphenidate references

• Take ADHD self-assessment quiz