Psychosis with Coexisting Substance Misuse: The NICE Guideline on Assessment and Management in Adults and Young People
National Collaborating Centre for Mental Health (NCCMH)
Around 40% of people experiencing psychosis also misuse
substances at some point in their lives, which can lead to serious
health and social problems for the person and complicate their
This new guideline covers the assessment and management of adults
and young people (aged 14 years and older) who have a clinical
diagnosis of psychosis (schizophrenia, bipolar disorder or other
affective psychosis) and coexisting substance misuse (harmful use
of any psychotropic substance including alcohol and legal or
Although separate NICE guidelines have been developed for the
management of schizophrenia, bipolar disorder and drug and alcohol
misuse, the importance of this new guideline on psychosis and
substance misuse is in offering advice on how to integrate
treatment for people with these commonly coexisting
The guideline includes comprehensive reviews of assessment, care
pathways and service delivery models, psychological and
pharmacological interventions for both conditions, and treatment
and services for young people.
Readership: All mental health professionals,
especially those working in substance misuse services.
List of the other NICE mental health
NICE Mental Health Guidelines
These guidelines from NICE set out clear
recommendations, based on the best available evidence, for health
care professionals on how to work with and implement physical,
psychological and service-level interventions for people with
various mental health conditions.
The book contains the full guidelines that cannot be obtained
in print anywhere else. It brings together all of the evidence that
led to the recommendations made, detailed explanations of the
methodology behind their preparation, plus an overview of the
condition covering detection, diagnosis and assessment, and the
full range of treatment and care approaches.
The accompanying free CD-ROM contains all the data used as
- Included and excluded studies.
- Profile tables that summarise both the quality of the evidence
and the results of the evidence synthesis.
- All meta-analytical data, presented as forest plots.
- Detailed information about how to use and interpret forest
- Psychosis with coexisting substance misuse
- Method used to develop this guideline
- Experience of care
- Assessment and care pathways
- Service delivery models
- Psychological and psychosocial interventions
- Pharmacological and physical interventions
- Young people with psychosis and coexisting substance
- Summary of recommendations