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Raj Persaud in conversation with Katherine Keyes on her research into the unexpected death of a loved one.
Katherine Keyes is Associate Professor of Epidemiology Columbia
University and, with several colleagues, has published a study in
the American Journal of Psychiatry investigating what happens when
people suffer one of the worst stresses of all - the unexpected
death of a loved one.
The Burden of Loss:
Unexpected Death of a Loved One and Psychiatric Disorders
Across the Life Course in a National Study.
Katherine M. Keyes, Ph.D.; Charissa Pratt,
M.P.H.; Sandro Galea, M.D., Dr.P.H.; Katie A. McLaughlin, Ph.D.;
Karestan C. Koenen, Ph.D.; M. Katherine Shear, M.D.
Am J Psychiatry 2014;171:864-871.
Objective Unexpected death of a loved
one is common and associated with subsequent elevations in symptoms
of multiple forms of psychopathology. Determining whether this
experience predicts novel onset of psychiatric disorders and
whether these associations vary across the life course has
important clinical implications. The authors examined associations
of a loved one’s unexpected death with first onset of common
anxiety, mood, and substance use disorders in a population-based
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