President's Lecture - Early detection of possible psychosis in young people

13Mar

Evening event

Timings 6.30pm-8pm
Location 21 Prescot St, London, United Kingdom, E1 8BB
Entry fee£5
Book now
President's Lecture - Early detection of possible psychosis in young people

Event Information

Dr Lawrence Yang will be giving a lecture entitled Early detection of possible psychosis in young people: is Stigma linked with symptoms or the At Risk Identification.

The clinical high-risk state for psychosis syndrome (CHR) offers substantial potential benefits in identifying and treating at-risk youth at the earliest signs of psychosis.

Early treatment might lead to decreased symptoms, thus reducing stigma related to symptoms. However, stigma of the CHR state for psychosis designation could initiate further stigma through the label of risk for psychosis among identified young people.

We studied 170 CHR state for psychosis individuals in a major, NIH-funded longitudinal study at 3 US centres from 2012 to 2017.

Labelling-related measures of stigma (e.g., “shame of being identified as at psychosis-risk”) adapted to the CHR group, and a parallel measure of symptom-related stigma (e.g., “shame of the symptoms associated with CHR”) were administered.

These measures were examined in relation to outcomes such as self-esteem, quality of life, social functioning and loss of social networks.

We confirmed the conventional wisdom that stigma related to symptoms was somewhat more strongly associated with most outcomes when compared with stigma related to the risk-label. 

Stigma related to symptoms remained a significant predictor of self-esteem, quality of life, and social network loss even after accounting for stigma related to the risk-label and the effects of covariates. Yet stigma related to the risk-label was still associated with several outcomes (self-esteem and social network loss) once we factored in stigma related to symptoms.

The lecture will place this study in the context of the knowns of stigma research.

Our findings indicate that CHR services should address stigma associated with symptoms quickly at first identification, given their negative impacts on outcomes.

Dr Yang will lead a discussion on how we might integrate best evidence into designing services for young people who may develop psychosis.


The event will take place at the Royal College of Psychiatrists, 21 Prescot Street, London E1 8BB. Take a look at a map and directions to help plan your journey.

The Citymapper website/app can help you plan your route within London, giving the best walking, cycling, bus and tube routes available. Use postcode E1 8BB as your destination.

Dr. Lawrence Yang is an Associate Professor of Social and Behavioural Sciences at NYU- College of Global Public Health. Dr Yang directs the Global Mental Health and Stigma Program at the College of Global Public Health.He is also an Adjunct Associate Professor of Epidemiology at Columbia University, where he was faculty for 11 years.

Dr. Yang received his Ph.D. in clinical psychology from Boston University and completed his clinical training at Harvard Medical School. Dr. Yang’s research focuses on the social factors that influence course of schizophrenia, and he has received training in clinical psychology, anthropology, and psychiatric epidemiology.

First, from his National Institutes of Mental Health K-award, he has formulated theoretical work on how culture relates to stigma and implementing interventions for Chinese immigrants with psychosis in New York City. Second, Dr. Yang is PI of a 5-year National Institutes of Mental Health R01 grant examining the neurocognitive and social cognitive underpinnings of the new "clinical high risk state for psychosis" designation, a potentially transformative new syndrome to detect psychotic signs before symptoms develop into a full psychotic disorder. Third, Dr. Yang has extensive research in global mental health.

He has received an R01 examining the cognition in the ‘natural state’ of psychosis in a large untreated, community sample of individuals with psychosis (n=400), who have not yet received any antipsychotic medications, compared with a treated sample (n=400) and healthy controls (n=400) in China. He also leads an evaluation of barriers and facilitators to mental health intervention scale-up in Latin America (Chile, Brazil and Argentina) via a U19 National Institutes of Mental Health Hub Grant. He has over one hundred publications, including publications in the British Journal of Psychiatry and The Lancet. Dr. Yang has received eight Early Career Awards, six of which are national, for his work.

Event Location

Location: 21 Prescot St, London, E1 8BB