Katherine Clarke

Katherine joined the NCCMH in 2024 from UCL, where she coordinated ODDESSI (Open Dialogue: Development and Evaluation of a Social Network Intervention for Severe Mental Illness), a large-scale programme of research into crisis and continuing mental health care within the NHS. ODDESSI has a focus on Open Dialogue, which incorporates people’s social networks into their care. Katherine has worked in research into the effectiveness of healthcare innovations for the last 15 years, with a particular focus on wellbeing and the long-term preservation of mental health. Projects include a large cluster-randomised trial of centralised and specialist early intervention for psychosis, an evaluation of the national expansion of IAPT services to reach more people with long-term physical health problems, and an individually randomised feasibility trial of a novel wellbeing intervention.

Key publications

Pilling S, Clarke K, Parker G., James K, Landau S, Weaver T, et al. Open Dialogue compared to treatment as usual for adults experiencing a mental health crisis: Protocol for the ODDESSI multi-site cluster randomised controlled trial. Contemporary Clinical Trials. 2022;113:106664. doi: https://doi.org/10.1016/j.cct.2021.106664

Clarke K, Furmaniak K, Pilling S. IAPT-LTC Early Implementers Programme. Report on the implementation and process evaluation of Wave 1 early implementer sites. London: NCCMH; 2018.

Clarke K, Mayo-Wilson E, Kenny J, Pilling S. Can non-pharmacological interventions prevent relapse in adults who have recovered from depression? A systematic review and meta-analysis of randomised controlled trials. Clinical Psychology Review. 2015;39:58–70. doi: http://doi.org/10.1016/j.cpr.2015.04.002